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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNH7
All Species:
26.06
Human Site:
S1127
Identified Species:
71.67
UniProt:
Q9NS40
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NS40
NP_150375.2
1196
135000
S1127
L
K
S
K
E
S
L
S
S
G
V
H
L
N
T
Chimpanzee
Pan troglodytes
XP_525954
1196
134979
S1127
L
K
S
K
E
S
L
S
S
G
V
H
L
N
T
Rhesus Macaque
Macaca mulatta
XP_001097904
1195
134865
S1126
L
K
S
K
E
S
L
S
S
G
V
H
L
N
T
Dog
Lupus familis
XP_535934
1197
134439
S1128
L
K
S
K
E
S
L
S
S
G
V
H
L
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER47
1195
135008
S1126
L
Q
S
K
E
S
L
S
S
G
R
R
L
N
T
Rat
Rattus norvegicus
O54852
1195
134882
S1126
L
K
S
K
E
S
L
S
S
G
K
R
L
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511873
1200
135504
S1131
L
K
S
K
E
S
L
S
S
G
V
H
L
N
T
Chicken
Gallus gallus
Q9PT84
526
59775
L458
S
K
G
C
L
R
A
L
A
M
K
F
K
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688778
1181
131984
D1112
V
P
I
E
T
T
S
D
V
T
A
A
T
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
95.7
N.A.
94.1
94.3
N.A.
90
38.6
N.A.
66.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.6
97.6
N.A.
96.4
96.5
N.A.
93.9
41.2
N.A.
77
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
100
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
100
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
12
0
12
12
0
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
78
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
78
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
78
0
78
0
0
0
0
0
0
23
0
12
0
0
% K
% Leu:
78
0
0
0
12
0
78
12
0
0
0
0
78
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
78
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
0
12
23
0
0
0
% R
% Ser:
12
0
78
0
0
78
12
78
78
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
12
12
0
0
0
12
0
0
12
12
89
% T
% Val:
12
0
0
0
0
0
0
0
12
0
56
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _